Obviously, drug companies are not happy with this practice, because it cuts into their profits. But there are legitimate medical concerns with pill-splitting. Splitting your pill exactly in half is not easy - and it's even more difficult for people with cognitive impairment, visual impairment, or arthritis. If someone splits their pill inaccurately, it could lead to overdoses or under-doses of medication.
Still, there are a number of medications where it's okay if the pill isn't split exactly in half. For example, studies show that there is no difference in the cholesterol level or liver function of patients who split the cholesterol lowering medication Zocor and patients who take the same dosage in single pills.
